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Souls are the spirits you can get if you kill a human or a zombie in an infection/zombie deathmatch game, you will get 100-150 souls for each kill. You can use souls to upgrade the number of points assigned to your abilities (e.g. lifesteal, strength). You can also use souls to add more points to attributes of your two active abilities (e.g. invisibility, heal aura). You lose souls if you die, and any upgrades purchased with the lost souls will be undone.